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Reperfusion Injury Summary

Description: Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.

Also Known As: Injury, Ischemia-Reperfusion; Injury, Reperfusion; Reperfusion Damage; Damage, Reperfusion; Damages, Reperfusion Show All >>

Networked: 15492 relevant articles (1694 outcomes, 2100 trials/studies) for this Disease

Key Drugs and Agents for Reperfusion Injury

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Nitric Oxide (Nitrogen Monoxide) : 46 outcomes 55 studies in 534 results : FDA 1
  2. Oxygen : 39 outcomes 79 studies in 720 results : IBA
  3. Superoxide Dismutase : 33 outcomes 27 studies in 199 results : IBA
  4. Melatonin : 25 outcomes 20 studies in 125 results : IBA
  5. Adenosine Triphosphate (ATP) : 24 outcomes 29 studies in 237 results : IBA
  6. Adenosine : 23 outcomes 26 studies in 198 results : FDA 19 Generic
  7. Phosphotransferases (Kinase) : 21 outcomes 26 studies in 225 results : IBA
  8. Acetylcysteine (Siran) : 20 outcomes 23 studies in 109 results : FDA 17 Generic
  9. Allopurinol (Remid) : 19 outcomes 22 studies in 120 results : FDA 25 Generic
  10. Retinaldehyde (Retinal) : 18 outcomes 36 studies in 168 results : IBA
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Diseases Related to Reperfusion Injury

  1. Ischemia
  2. Myocardial Ischemia (Ischemic Heart Diseases)
  3. Brain Ischemia (Cerebral Ischemia)
  4. Inflammation
  5. Myocardial Infarction
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Key Therapies for Reperfusion Injury

Efficacy Chart >>
  1. Transplants (Transplant) : 72 outcomes 67 studies in 893 results
  2. Transplantation (Transplant Recipients) : 38 outcomes 40 studies in 514 results
  3. Lung Transplantation : 27 outcomes 23 studies in 264 results
  4. Homologous Transplantation (Allograft) : 24 outcomes 25 studies in 322 results
  5. Ischemic Postconditioning : 24 outcomes 18 studies in 167 results
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