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Discitis Summary

Description: Inflammation of an intervertebral disk or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

Also Known As: Diskitis; Spondylodiskitis; Discitides; Diskitides; Spondylodiscitides Show All >>

Networked: 493 relevant articles (34 outcomes, 39 trials/studies) for this Disease

Key Drugs and Agents for Discitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Anti-Bacterial Agents (Antibiotics) : 2 outcomes 6 studies in 52 results : IBA
  2. Vancomycin : 2 outcomes 4 studies in 8 results : FDA 23 Generic
  3. linezolid (Zyvox) : 2 outcomes 1 study in 7 results : FDA 7
  4. Fluconazole (Zonal) : 2 outcomes in 5 results : FDA 41 Generic
  5. Cefazolin (Ancef) : 1 outcome 3 studies in 9 results : FDA 35 Generic
  6. C-Reactive Protein : 1 outcome 2 studies in 12 results : IBA
  7. Ofloxacin (Levofloxacin) : 1 outcome 1 study in 2 results : FDA 49 Generic
  8. Rifampin (Rifampicin) : 1 outcome 1 study in 1 result : FDA 13 Generic
  9. polylactic acid-polyglycolic acid copolymer (PLGA) : 1 outcome 1 study in 1 result : IBA
  10. Gentamicins (Gentamicin) : 1 outcome in 4 results : FDA 63 Generic
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Diseases Related to Discitis

  1. Abscess
  2. Infection
  3. Epidural Abscess
  4. Osteomyelitis
  5. Meningitis
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Key Therapies for Discitis

Efficacy Chart >>
  1. Debridement : 7 outcomes 6 studies in 58 results
  2. Transplants (Transplant) : 2 outcomes 2 studies in 33 results
  3. Drug Therapy (Chemotherapy) : 2 outcomes in 11 results
  4. Diskectomy (Discectomy) : 1 outcome 1 study in 38 results
  5. Curettage : 1 outcome 1 study in 4 results
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