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Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome) Summary

Description: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Also Known As: Wolf-Parkinson-White Syndrome; Syndrome, Wolff-Parkinson-White; Anomalous Ventricular Excitation Syndrome; Auriculoventricular Accessory Pathway Syndrome; False Bundle-Branch Block Syndrome Show All >>

Networked: 677 relevant articles (47 outcomes, 51 trials/studies) for this Disease

Key Drugs and Agents for Wolff-Parkinson-White Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Amiodarone (Amiodarona) : 7 outcomes 3 studies in 49 results : FDA 4 Generic
  2. Adenosine : 5 outcomes 3 studies in 36 results : FDA 19 Generic
  3. Flecainide (Tambocor) : 5 outcomes 2 studies in 33 results : FDA 7 Generic
  4. Sotalol (Sotalol Hydrochloride) : 4 outcomes 4 studies in 15 results : FDA 18 Generic
  5. Propafenone (Rythmol) : 4 outcomes 2 studies in 25 results : FDA 8 Generic
  6. Verapamil (Calan) : 3 outcomes 1 study in 32 results : FDA 64 Generic
  7. Ajmaline (Wolfina) : 2 outcomes 3 studies in 32 results : FDA 1
  8. Anti-Arrhythmia Agents : 2 outcomes 1 study in 12 results : IBA
  9. Encainide : 2 outcomes 1 study in 11 results : IBA
  10. Procainamide (Procan) : 2 outcomes in 35 results : FDA 75 Generic
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Diseases Related to Wolff-Parkinson-White Syndrome

  1. Atrial Fibrillation
  2. Tachycardia (Tachyarrhythmias)
  3. Supraventricular Tachycardia
  4. Atrioventricular Nodal Reentry Tachycardia (AV Nodal Reentrant Tachycardia)
  5. Atrial Flutter (Flutter, Atrial)
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Key Therapies for Wolff-Parkinson-White Syndrome

Efficacy Chart >>
  1. Catheters : 4 outcomes 9 studies in 41 results
  2. Electric Countershock (Cardioversion) : 2 outcomes 1 study in 19 results
  3. Electrodes (Electrode) : 1 outcome 4 studies in 20 results
  4. Coronary Artery Bypass (Coronary Artery Bypass Surgery) : 1 outcome 1 study in 5 results
  5. Cryosurgery : 1 outcome in 18 results
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