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von Willebrand Factor Summary

Description: A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Also Known As: Factor VIIIR-Ag; Factor VIIIR-RCo; Plasma Factor VIII Complex; Ristocetin Cofactor; Ristocetin-Willebrand Factor Show All >>

Networked: 4766 relevant articles (87 outcomes, 433 trials/studies) for this Bio-Agent

Key Diseases for which von Willebrand Factor is Relevant

  1. von Willebrand Diseases (von Willebrand's Disease) : 28 outcomes 67 studies in 764 results
  2. Hemorrhage : 8 outcomes 25 studies in 485 results
  3. Thrombosis (Thrombus) : 6 outcomes 21 studies in 436 results
  4. Thrombotic Thrombocytopenic Purpura : 6 outcomes 14 studies in 237 results
  5. Hemophilia A (Haemophilia) : 5 outcomes 13 studies in 139 results
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Drugs Related to von Willebrand Factor

  1. Factor VIII (Coagulation Factor VIII)
  2. Antigens
  3. Collagen
  4. von Willebrand Factor
  5. thymidine 5'-triphosphate (TTP)
  6. Deamino Arginine Vasopressin (Desmopressin)
  7. C-Reactive Protein
  8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  9. Tissue Plasminogen Activator (Alteplase)
  10. P-Selectin
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Therapies Related to von Willebrand Factor

  1. Plasma Exchange
  2. Homologous Transplantation (Allograft)
  3. Prostheses and Implants (Prosthesis)
  4. Transplants (Transplant)
  5. Peritoneal Dialysis
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