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Thioredoxins Summary

Description: Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.

Also Known As: Thioredoxin; Thioredoxin 1; Thioredoxin 2; Thioredoxin-1; Thioredoxin-2

Networked: 986 relevant articles (28 outcomes, 93 trials/studies) for this Bio-Agent

Key Diseases for which Thioredoxins is Relevant

  1. Myocarditis (Carditis) : 5 outcomes 1 study in 12 results
  2. Reperfusion Injury : 3 outcomes 2 studies in 31 results
  3. Inflammation : 2 outcomes 2 studies in 56 results
  4. Fibrosis (Cirrhosis) : 2 outcomes 2 studies in 10 results
  5. Pneumonia (Pneumonitis) : 2 outcomes in 4 results
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Drugs Related to Thioredoxins

  1. temocapril hydrochloride (temocapril)
  2. Thioredoxins
  3. Glutathione (Reduced Glutathione)
  4. Biological Markers (Surrogate Marker)
  5. adult T cell leukemia-derived factor
  6. NADPH Oxidase (NAD(P)H oxidase)
  7. Curcumin
  8. Reactive Oxygen Species (Oxygen Radicals)
  9. NF-kappa B (NF-kB)
  10. Antioxidants
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Therapies Related to Thioredoxins

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Atherectomy
  4. Ligation
  5. Lung Transplantation
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