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Thalidomide (Thalomid) Summary

Description: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppresive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.

Also Known As: Thalomid; Celgene Brand of Thalidomide; Sedoval; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-

Networked: 3480 relevant articles (542 outcomes, 683 trials/studies) for this Drug

Key Diseases for which Thalidomide is Relevant

  1. Multiple Myeloma : 191 outcomes 201 studies in 1014 results
  2. Neoplasms (Cancer) : 39 outcomes 65 studies in 383 results
  3. Crohn Disease (Crohn's Disease) : 22 outcomes 16 studies in 83 results
  4. Erythema Nodosum : 22 outcomes 10 studies in 125 results
  5. Leprosy (Hansen's Disease) : 16 outcomes 9 studies in 128 results
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Drugs Related to Thalidomide

  1. bortezomib (Velcade)
  2. lenalidomide (CC 5013)
  3. Dexamethasone (Maxidex)
  4. Cyclophosphamide (Cytoxan)
  5. Melphalan (Alkeran)
  6. Prednisone (Sone)
  7. Proteasome Endopeptidase Complex (Proteasome)
  8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  9. Adrenal Cortex Hormones (Corticosteroids)
  10. Prednisolone (Predate)
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Therapies Related to Thalidomide

  1. Drug Therapy (Chemotherapy)
  2. Stem Cell Transplantation
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  4. Radiotherapy
  5. Aftercare (After-Treatment)
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