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Syringomyelia (Morvan's Disease) Summary

Description: Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)

Also Known As: Morvan's Disease; Syringomyelus; Myelosyringosis; Hydrosyringomyelias; Morvan Diseases Show All >>

Networked: 540 relevant articles (33 outcomes, 39 trials/studies) for this Disease

Key Drugs and Agents for Syringomyelia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Familial spinal arachnoiditis : 1 outcome 2 studies in 32 results : IBA
  2. Iron : 1 outcome in 2 results : IBA
  3. Penicillins (Penicillin) : 1 outcome in 1 result : FDA 1
  4. Metrizamide : 4 studies in 25 results : FDA 1
  5. Kaolin : 4 studies in 25 results : IBA
  6. SAS : 2 studies in 5 results : IBA
  7. tebufenozide (Mimic) : 1 study in 9 results : IBA
  8. Substance P : 1 study in 3 results : IBA
  9. Hormones : 1 study in 2 results : IBA
  10. Calcitonin Gene-Related Peptide : 1 study in 1 result : IBA
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Diseases Related to Syringomyelia

  1. Scoliosis
  2. Hydrocephalus (Hydrocephaly)
  3. Pain (Aches)
  4. Encephalocele (Encephalocele, Frontal)
  5. Meningitis
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Key Therapies for Syringomyelia

Efficacy Chart >>
  1. Decompression : 22 outcomes 17 studies in 168 results
  2. Ventriculostomy : 2 outcomes 1 study in 22 results
  3. Laminectomy : 2 outcomes 1 study in 20 results
  4. Surgical Decompression : 2 outcomes 1 study in 11 results
  5. Craniotomy : 2 outcomes in 7 results
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