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Spinal Cord Compression Summary

Description: Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.

Also Known As: Extramedullary Spinal Cord Compression; Spinal Cord Compression, Extramedullary; Compression, Spinal Cord; Compressions, Spinal Cord; Compressive Myelopathy Show All >>

Networked: 1016 relevant articles (64 outcomes, 91 trials/studies) for this Disease

Key Drugs and Agents for Spinal Cord Compression

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Diphosphonates : 2 outcomes 2 studies in 13 results : IBA
  2. Glial Cell Line-Derived Neurotrophic Factor (GDNF) : 2 outcomes 1 study in 2 results : IBA
  3. Adrenal Cortex Hormones (Corticosteroids) : 2 outcomes in 13 results : IBA
  4. Dexamethasone (Maxidex) : 1 outcome 4 studies in 26 results : FDA 77 Generic
  5. zoledronic acid (zoledronate) : 1 outcome 3 studies in 4 results : FDA 13
  6. Cholecalciferol (Vitamin D3) : 1 outcome 2 studies in 2 results : FDA 5
  7. Methylprednisolone : 1 outcome 1 study in 10 results : FDA 18 Generic
  8. Radioisotopes (Radionuclides) : 1 outcome 1 study in 2 results : IBA
  9. Unsaturated Fatty Acids (Polyunsaturated Fatty Acids) : 1 outcome 1 study in 2 results : IBA
  10. Botulinum Toxins (Botulinum Toxin) : 1 outcome 1 study in 2 results : IBA
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Diseases Related to Spinal Cord Compression

  1. Neoplasms (Cancer)
  2. Neoplasm Metastasis (Metastasis)
  3. Spinal Cord Injuries (Spinal Cord Injury)
  4. Spontaneous Fractures (Pathological Fracture)
  5. Pain (Aches)
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Key Therapies for Spinal Cord Compression

Efficacy Chart >>
  1. Radiotherapy : 17 outcomes 29 studies in 222 results
  2. Surgical Decompression : 6 outcomes 6 studies in 50 results
  3. Laminectomy : 5 outcomes 3 studies in 85 results
  4. Decompression : 3 outcomes 6 studies in 104 results
  5. Drug Therapy (Chemotherapy) : 3 outcomes 4 studies in 40 results
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