Search Login Register

Systemic Scleroderma (Systemic Sclerosis) Summary

Description: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Also Known As: Systemic Sclerosis; Scleroderma, Systemic; Sclerosis, Systemic

Networked: 4265 relevant articles (178 outcomes, 495 trials/studies) for this Disease

Key Drugs and Agents for Systemic Scleroderma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclophosphamide (Cytoxan) : 19 outcomes 17 studies in 85 results : FDA 10 Generic
  2. Idiopathic pulmonary hypertension : 12 outcomes 29 studies in 290 results : IBA
  3. bosentan (Tracleer) : 11 outcomes 18 studies in 84 results : FDA 1
  4. Iloprost (Ventavis) : 7 outcomes 16 studies in 57 results : FDA 1
  5. Endothelin Receptors (Endothelin Receptor) : 6 outcomes 5 studies in 34 results : IBA
  6. imatinib (Gleevec) : 5 outcomes 7 studies in 24 results : FDA 3
  7. Cyclosporine (Ciclosporin) : 5 outcomes 2 studies in 26 results : FDA 20 Generic
  8. Antibodies : 4 outcomes 28 studies in 404 results : IBA
  9. Penicillamine (Cuprimine) : 4 outcomes 10 studies in 62 results : FDA 2
  10. Collagen Type I (Type I Collagen) : 4 outcomes 4 studies in 38 results : IBA
Show All >>

Diseases Related to Systemic Scleroderma

  1. Interstitial Lung Diseases (Interstitial Lung Disease)
  2. Ulcer
  3. Fibrosis (Cirrhosis)
  4. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  5. Sclerosis
Show All >>

Key Therapies for Systemic Scleroderma

Efficacy Chart >>
  1. Photopheresis : 4 outcomes 8 studies in 31 results
  2. Transplants (Transplant) : 4 outcomes 7 studies in 40 results
  3. Stem Cell Transplantation : 3 outcomes 10 studies in 55 results
  4. Phototherapy (Light Therapy) : 3 outcomes 3 studies in 11 results
  5. Lasers (Laser) : 2 outcomes 8 studies in 44 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.