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Messenger RNA (mRNA) Summary

Description: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Also Known As: mRNA; Poly(A) Tail; RNA, Messenger; Non-Polyadenylated mRNA; Poly(A) RNA Show All >>

Networked: 72161 relevant articles (1097 outcomes, 7031 trials/studies) for this Bio-Agent

Key Diseases for which Messenger RNA is Relevant

  1. Neoplasms (Cancer) : 160 outcomes 1043 studies in 13807 results
  2. Infection : 70 outcomes 263 studies in 4252 results
  3. Inflammation : 42 outcomes 150 studies in 2000 results
  4. Body Weight (Weight, Body) : 37 outcomes 41 studies in 869 results
  5. Fibrosis (Cirrhosis) : 33 outcomes 67 studies in 1221 results
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Drugs Related to Messenger RNA

  1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  2. Messenger RNA (mRNA)
  3. Cytokines
  4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  5. Interleukin-6 (Interleukin 6)
  6. Interleukin-10 (Interleukin 10)
  7. DNA (Deoxyribonucleic Acid)
  8. Insulin (Novolin)
  9. Small Interfering RNA (siRNA)
  10. Proteins (Proteins, Gene)
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Therapies Related to Messenger RNA

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Aftercare (After-Treatment)
  4. Oral Administration
  5. Radiotherapy
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