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Rhabdomyosarcoma Summary

Description: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)

Also Known As: Rhabdomyosarcomas

Networked: 2727 relevant articles (107 outcomes, 348 trials/studies) for this Disease

Key Drugs and Agents for Rhabdomyosarcoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Doxorubicin (Adriamycin) : 6 outcomes 12 studies in 48 results : FDA 12 Generic
  2. Cyclophosphamide (Cytoxan) : 5 outcomes 22 studies in 59 results : FDA 10 Generic
  3. Desmin : 4 outcomes 9 studies in 113 results : IBA
  4. Antibodies : 4 outcomes 1 study in 61 results : IBA
  5. Vincristine (Oncovin) : 3 outcomes 26 studies in 87 results : FDA 17 Generic
  6. Ifosfamide : 3 outcomes 15 studies in 37 results : FDA 7 Generic
  7. irinotecan (Camptosar) : 3 outcomes 7 studies in 20 results : FDA 19 Generic
  8. Cisplatin (Platino) : 3 outcomes 6 studies in 24 results : FDA 6 Generic
  9. Anthracyclines : 3 outcomes in 3 results : IBA
  10. Dactinomycin (Ac-De) : 2 outcomes 20 studies in 54 results : FDA 2 Generic
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Diseases Related to Rhabdomyosarcoma

  1. Neoplasms (Cancer)
  2. Sarcoma (Soft Tissue Sarcoma)
  3. Neoplasm Metastasis (Metastasis)
  4. Neuroblastoma
  5. Ewing's Sarcoma (Sarcoma, Ewing)
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Key Therapies for Rhabdomyosarcoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 45 outcomes 72 studies in 446 results
  2. Radiotherapy : 12 outcomes 34 studies in 198 results
  3. Heterologous Transplantation (Xenotransplantation) : 7 outcomes 15 studies in 122 results
  4. Brachytherapy : 2 outcomes 2 studies in 31 results
  5. Combined Modality Therapy : 2 outcomes in 11 results
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