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Prothrombin (Factor II) Summary

Description: A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

Also Known As: Factor II; Blood Coagulation Factor II; Differentiation Reversal Factor; Factor II, Coagulation; Factor, Differentiation Reversal Show All >>

Networked: 3772 relevant articles (73 outcomes, 332 trials/studies) for this Bio-Agent

Key Diseases for which Prothrombin is Relevant

  1. Hemorrhage : 20 outcomes 37 studies in 377 results
  2. Hemophilia A (Haemophilia) : 10 outcomes 11 studies in 99 results
  3. Thrombosis (Thrombus) : 7 outcomes 30 studies in 459 results
  4. Liver Diseases (Liver Disease) : 4 outcomes 3 studies in 70 results
  5. Hypoprothrombinemias (Prothrombin Deficiency) : 4 outcomes 3 studies in 59 results
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Drugs Related to Prothrombin

  1. factor V Leiden
  2. recombinant FVIIa (rFVIIa)
  3. Bilirubin
  4. Factor V (Coagulation Factor V)
  5. Factor VIII (Coagulation Factor VIII)
  6. Factor VIIa (Activated Factor VII)
  7. Fibrinogen (Factor I)
  8. Thromboplastin (Tissue Factor)
  9. Serum Albumin
  10. Thrombin
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Therapies Related to Prothrombin

  1. Aftercare (After-Treatment)
  2. Blood Transfusion (Blood Transfusions)
  3. Liver Transplantation
  4. Minor Surgical Procedures (Minor Surgery)
  5. Drug Therapy (Chemotherapy)
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