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Protein-Tyrosine Kinases (Tyrosine Kinase) Summary

Description: Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.

Also Known As: Tyrosine Kinase; Protein-Tyrosine Kinase; Kinase, Tyrosine; Tyrosine Protein Kinases; Tyrosine-Specific Protein Kinases Show All >>

Networked: 12167 relevant articles (840 outcomes, 1228 trials/studies) for this Bio-Agent

Key Diseases for which Protein-Tyrosine Kinases is Relevant

  1. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) : 180 outcomes 161 studies in 1392 results
  2. Neoplasms (Cancer) : 151 outcomes 306 studies in 3177 results
  3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) : 139 outcomes 69 studies in 1391 results
  4. Renal Cell Carcinoma (Grawitz Tumor) : 51 outcomes 41 studies in 397 results
  5. Lung Neoplasms (Lung Cancer) : 50 outcomes 60 studies in 609 results
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Drugs Related to Protein-Tyrosine Kinases

  1. Epidermal Growth Factor Receptor (EGF Receptor)
  2. imatinib (Gleevec)
  3. gefitinib (Iressa)
  4. erlotinib (CP 358,774)
  5. sunitinib (Sutent)
  6. sorafenib (BAY 43-9006)
  7. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
  8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  9. lapatinib (GW572016)
  10. Phosphotransferases (Kinase)
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Therapies Related to Protein-Tyrosine Kinases

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Radiotherapy
  4. Therapeutics
  5. Transplants (Transplant)
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