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Protein C
Summary
Description:
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Key Diseases for which Protein C is
Relevant
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Sepsis (Septicemia)
:
71 outcomes 168 studies in 678 results
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Septic Shock (Toxic Shock Syndrome)
:
12 outcomes 23 studies in 136 results
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Protein C Deficiency
:
9 outcomes 11 studies in 215 results
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Inflammation
:
8 outcomes 20 studies in 236 results
-
Hemorrhage
:
7 outcomes 21 studies in 99 results
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Drugs Related to Protein C
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drotrecogin alfa activated (Xigris)
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Antithrombin III
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Heparin (Liquaemin)
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Protein S
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Dacarbazine (DIC)
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lipoprotein-associated coagulation inhibitor (TFPI)
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Anticoagulants
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Antigens
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Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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Norepinephrine (Noradrenaline)
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Therapies Related to Protein C
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Resuscitation
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Catheters
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Transplants (Transplant)
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Artificial Respiration (Mechanical Ventilation)
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Transplantation (Transplant Recipients)
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