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Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal) Summary

Description: A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.

Also Known As: Polyposis, Hamartomatous Intestinal; Polyps-and-Spots Syndrome; Syndrome, Peutz-Jeghers; Lentiginosis, Perioral; Periorificial Lentiginosis Syndrome Show All >>

Networked: 291 relevant articles (5 outcomes, 10 trials/studies) for this Disease

Key Drugs and Agents for Peutz-Jeghers Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Sirolimus (Rapamycin) : 1 outcome in 4 results : FDA 2
  2. inhibin B : 1 outcome in 2 results : IBA
  3. Inhibins (Inhibin) : 1 outcome in 1 result : IBA
  4. inhibin A : 1 outcome in 1 result : IBA
  5. Barium : 3 studies in 6 results : IBA
  6. Protein Kinases (Protein Kinase) : 1 study in 15 results : IBA
  7. Threonine (L-Threonine) : 1 study in 13 results : FDA 30
  8. Serine (L-Serine) : 1 study in 13 results : FDA 16
  9. Cyclooxygenase 2 (Cyclooxygenase-2) : 1 study in 4 results : IBA
  10. Turcot syndrome : 1 study in 3 results : IBA
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Diseases Related to Peutz-Jeghers Syndrome

  1. Polyps
  2. Neoplasms (Cancer)
  3. Granulosa Cell Tumor
  4. Hamartoma
  5. Gynecomastia
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Key Therapies for Peutz-Jeghers Syndrome

Efficacy Chart >>
  1. Solid-State Lasers : 1 outcome 2 studies in 8 results
  2. Laparotomy : 1 outcome in 15 results
  3. Chemoprevention : 1 outcome in 2 results
  4. Ligation : 2 results
  5. Lasers (Laser) : 2 results
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