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Polyarteritis Nodosa (Periarteritis Nodosa) Summary

Description: A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.

Also Known As: Periarteritis Nodosa; Arteritides, Necrotizing; Arteritis, Necrotizing; Essential Polyarteritides; Necrotizing Arteritides Show All >>

Networked: 806 relevant articles (45 outcomes, 23 trials/studies) for this Disease

Key Drugs and Agents for Polyarteritis Nodosa

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclophosphamide (Cytoxan) : 6 outcomes 4 studies in 45 results : FDA 10 Generic
  2. Interferon-alpha (Interferon Alfa) : 6 outcomes in 19 results : FDA 2
  3. Prednisolone (Predate) : 5 outcomes in 15 results : FDA 55 Generic
  4. Adrenal Cortex Hormones (Corticosteroids) : 3 outcomes 4 studies in 32 results : IBA
  5. Immunosuppressive Agents (Immunosuppressants) : 3 outcomes in 16 results : IBA
  6. Lamivudine (3TC) : 3 outcomes in 13 results : FDA 62
  7. Antineutrophil Cytoplasmic Antibodies (ANCA) : 2 outcomes 3 studies in 86 results : IBA
  8. Steroids : 2 outcomes 1 study in 19 results : IBA
  9. rituximab (Mabthera) : 2 outcomes 1 study in 5 results : FDA 3
  10. Intravenous Immunoglobulins (IVIG) : 2 outcomes in 10 results : FDA 1
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Diseases Related to Polyarteritis Nodosa

  1. Vasculitis (Vasculitides)
  2. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  3. Churg-Strauss Syndrome (Allergic Angiitis)
  4. Glomerulonephritis
  5. Hepatitis B
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Key Therapies for Polyarteritis Nodosa

Efficacy Chart >>
  1. Plasma Exchange : 7 outcomes 2 studies in 28 results
  2. Kidney Transplantation : 2 outcomes in 4 results
  3. Angioplasty (Angioplasty, Transluminal) : 1 outcome in 4 results
  4. Amputation : 1 outcome in 4 results
  5. Sympathectomy (Sympathectomies) : 1 outcome in 1 result
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