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Penile Induration (Peyronie's Disease) Summary

Description: A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.

Also Known As: Peyronie's Disease; Peyronie Disease; Penile Fibromatosis; Plastic Induration of the Penis; Cavernitides, Fibrous Show All >>

Networked: 622 relevant articles (56 outcomes, 101 trials/studies) for this Disease

Key Drugs and Agents for Penile Induration

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Verapamil (Calan) : 13 outcomes 13 studies in 42 results : FDA 64 Generic
  2. Interferons : 7 outcomes 4 studies in 15 results : IBA
  3. Vitamin E : 4 outcomes 3 studies in 17 results : FDA 13 Generic
  4. Dexamethasone (Maxidex) : 4 outcomes 2 studies in 11 results : FDA 77 Generic
  5. Microbial Collagenase (Clostridiopeptidase A) : 3 outcomes 14 studies in 23 results : IBA
  6. Colchicine : 3 outcomes 5 studies in 11 results : FDA 13 Generic
  7. Interferon-alpha (Interferon Alfa) : 3 outcomes 1 study in 7 results : FDA 2
  8. Pentoxifylline (Trental) : 2 outcomes 3 studies in 8 results : FDA 11 Generic
  9. Tamoxifen : 2 outcomes 2 studies in 4 results : FDA 12 Generic
  10. Lidocaine (Xylocaine) : 2 outcomes 2 studies in 4 results : FDA 168 Generic
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Diseases Related to Penile Induration

  1. Pain (Aches)
  2. Erectile Dysfunction
  3. Congenital Abnormalities (Deformity)
  4. Penile Neoplasms (Penile Cancer)
  5. Infection
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Key Therapies for Penile Induration

Efficacy Chart >>
  1. Penile Prosthesis (Penile Implants) : 5 outcomes 10 studies in 66 results
  2. Intralesional Injections : 3 outcomes 6 studies in 21 results
  3. Prostheses and Implants (Prosthesis) : 2 outcomes 2 studies in 23 results
  4. Transplants (Transplant) : 1 outcome 5 studies in 96 results
  5. Injections : 1 outcome 5 studies in 22 results
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