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Papaverine Summary

Description: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.

Also Known As: Cerespan; Papaverine Hydrochloride; Pavabid; Pavatym; Hydrochloride, Papaverine Show All >>

Networked: 1002 relevant articles (68 outcomes, 87 trials/studies) for this Bio-Agent

Key Diseases for which Papaverine is Relevant

  1. Erectile Dysfunction : 18 outcomes 30 studies in 230 results
  2. Spasm (Spasms) : 7 outcomes 8 studies in 74 results
  3. Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) : 6 outcomes 3 studies in 51 results
  4. Intracranial Vasospasm : 5 outcomes 2 studies in 69 results
  5. Hyperemia : 2 outcomes 6 studies in 48 results
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Drugs Related to Papaverine

  1. Alprostadil (Muse)
  2. Phentolamine (Z-Max)
  3. Diclofenac (SR 38)
  4. Adenosine
  5. Verapamil (Calan)
  6. Nitroglycerin (Dynamite)
  7. Vasodilator Agents (Vasodilators)
  8. Histamine (Histamine Dihydrochloride)
  9. Nimodipine (Modus)
  10. Nicardipine (Dagan)
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Therapies Related to Papaverine

  1. Transplants (Transplant)
  2. Intra-Arterial Infusions
  3. Angioplasty (Angioplasty, Transluminal)
  4. Balloon Angioplasty
  5. Resuscitation
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