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Neural Tube Defects
(Exencephaly)
Summary
Description:
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Also Known As:
Exencephaly; Diastematomyelia; Iniencephaly; Neural Tube Defect; Craniorachischisis Show All >>
Networked: 3208
relevant articles (103 outcomes,
316 trials/studies)
for this Disease
Key Drugs and Agents for Neural Tube Defects
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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Folic Acid (Vitamin M)
:
73 outcomes 157 studies in 1505 results
:
FDA 50
Generic
-
alpha-Fetoproteins (AFP)
:
11 outcomes 26 studies in 319 results
: IBA
-
Vitamins
:
7 outcomes 23 studies in 159 results
: IBA
-
Glucose (Dextrose)
:
3 outcomes 1 study in 20 results
:
FDA 175
Generic
-
Valproic Acid (Valproate, Semisodium)
:
2 outcomes 9 studies in 115 results
:
FDA 51
Generic
-
Acetylcholinesterase
:
2 outcomes 6 studies in 69 results
: IBA
-
Methionine (L-Methionine)
:
2 outcomes 1 study in 21 results
:
FDA 30
-
Inositol (Myoinositol)
:
2 outcomes in 20 results
: IBA
-
Aspirin (Acetylsalicylic Acid)
:
2 outcomes in 6 results
:
FDA 80
Generic
-
Pantothenic Acid (Calcium Pantothenate)
:
2 outcomes in 4 results
:
FDA 1
Show All >>
Diseases Related to Neural Tube Defects
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Congenital Abnormalities (Deformity)
-
Spinal Dysraphism (Spina Bifida)
-
Neural Tube Defects (Exencephaly)
-
Neoplasms (Cancer)
-
Heart Diseases (Heart Disease)
Show All >>
Key Therapies for Neural Tube Defects
Efficacy Chart >>
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Induced Hyperthermia (Thermotherapy)
:
1 outcome 4 studies in 8 results
-
Catheters
:
1 outcome 1 study in 2 results
-
Neonatal Intensive Care
:
1 outcome 1 study in 2 results
-
Aftercare (After-Treatment)
:
1 outcome in 7 results
-
Prenatal Care
:
1 outcome in 6 results
Show All >>
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