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Nephrotic Syndrome (Syndrome, Nephrotic) Summary

Description: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Also Known As: Syndrome, Nephrotic; Nephrotic Syndromes; Syndromes, Nephrotic

Networked: 6565 relevant articles (736 outcomes, 601 trials/studies) for this Disease

Key Drugs and Agents for Nephrotic Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclosporine (Ciclosporin) : 103 outcomes 37 studies in 390 results : FDA 20 Generic
  2. Cyclophosphamide (Cytoxan) : 67 outcomes 26 studies in 261 results : FDA 10 Generic
  3. Prednisolone (Predate) : 55 outcomes 27 studies in 195 results : FDA 55 Generic
  4. Prednisone (Sone) : 45 outcomes 23 studies in 212 results : FDA 119 Generic
  5. rituximab (Mabthera) : 39 outcomes 17 studies in 137 results : FDA 3
  6. Adrenal Cortex Hormones (Corticosteroids) : 32 outcomes 14 studies in 166 results : IBA
  7. Methylprednisolone : 30 outcomes 8 studies in 74 results : FDA 18 Generic
  8. Steroids : 28 outcomes 11 studies in 180 results : IBA
  9. Chlorambucil (Leukeran) : 26 outcomes 8 studies in 76 results : FDA 1
  10. Creatinine : 21 outcomes 11 studies in 190 results : IBA
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Diseases Related to Nephrotic Syndrome

  1. Proteinuria
  2. Membranous Glomerulonephritis (Membranous Nephropathy)
  3. Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
  4. Amyloidosis
  5. Glomerulonephritis
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Key Therapies for Nephrotic Syndrome

Efficacy Chart >>
  1. Aftercare (After-Treatment) : 18 outcomes 1 study in 51 results
  2. Drug Therapy (Chemotherapy) : 16 outcomes 5 studies in 72 results
  3. Transplantation (Transplant Recipients) : 15 outcomes 6 studies in 122 results
  4. Kidney Transplantation : 10 outcomes 6 studies in 154 results
  5. Plasmapheresis : 9 outcomes 3 studies in 38 results
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