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Mixed Connective Tissue Disease
(MCTD)
Summary
Description:
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
Also Known As:
MCTD; Syndrome, Sharp; Connective Tissue Disease, Mixed; Sharp Syndrome
Networked: 786
relevant articles (22 outcomes,
41 trials/studies)
for this Disease
Key Drugs and Agents for Mixed Connective Tissue Disease
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
-
Adrenal Cortex Hormones (Corticosteroids)
:
3 outcomes 1 study in 17 results
: IBA
-
Antibodies
:
2 outcomes 6 studies in 233 results
: IBA
-
Antineutrophil Cytoplasmic Antibodies (ANCA)
:
2 outcomes 1 study in 15 results
: IBA
-
Prednisolone (Predate)
:
2 outcomes in 17 results
:
FDA 55
Generic
-
Cyclophosphamide (Cytoxan)
:
2 outcomes in 14 results
:
FDA 10
Generic
-
Cyclosporine (Ciclosporin)
:
2 outcomes in 5 results
:
FDA 20
Generic
-
Autoantibodies
:
1 outcome 9 studies in 94 results
: IBA
-
bosentan (Tracleer)
:
1 outcome 2 studies in 5 results
:
FDA 1
-
Small Nuclear Ribonucleoproteins (snRNP)
:
1 outcome 1 study in 27 results
: IBA
-
DNA (Deoxyribonucleic Acid)
:
1 outcome 1 study in 20 results
: IBA
Show All >>
Diseases Related to Mixed Connective Tissue Disease
-
Mixed Connective Tissue Disease (MCTD)
-
Interstitial Lung Diseases (Interstitial Lung Disease)
-
Systemic Lupus Erythematosus (Libman-Sacks Disease)
-
Systemic Scleroderma (Systemic Sclerosis)
-
Glomerulonephritis
Show All >>
Key Therapies for Mixed Connective Tissue Disease
Efficacy Chart >>
-
Ketogenic Diet
:
1 outcome 1 study in 2 results
-
Drug Therapy (Chemotherapy)
:
1 outcome in 3 results
-
Thyroidectomy
:
1 outcome in 2 results
-
Aftercare (After-Treatment)
:
1 study in 2 results
-
Plasmapheresis
:
7 results
Show All >>
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