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Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) Summary

Description: An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)

Also Known As: Streptococcus pneumoniae Meningitis; Meningitis, Pneumococcal; Experimental Pneumococcal Meningitis; Meningitis, Pneumococcal, Experimental; Meningitis, Pneumococcal, Penicillin-Resistant Show All >>

Networked: 690 relevant articles (65 outcomes, 87 trials/studies) for this Disease

Key Drugs and Agents for Pneumococcal Meningitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Ceftriaxone (Ceftriaxon) : 17 outcomes 6 studies in 64 results : FDA 33 Generic
  2. Dexamethasone (Maxidex) : 14 outcomes 10 studies in 63 results : FDA 77 Generic
  3. Vancomycin : 13 outcomes 5 studies in 44 results : FDA 23 Generic
  4. Penicillins (Penicillin) : 10 outcomes 7 studies in 124 results : FDA 1
  5. Rifampin (Rifampicin) : 6 outcomes 2 studies in 19 results : FDA 13 Generic
  6. Daptomycin : 4 outcomes 6 studies in 13 results : FDA 1
  7. Ciprofloxacin (Cipro) : 3 outcomes 2 studies in 7 results : FDA 60 Generic
  8. meropenem (Merrem) : 3 outcomes 1 study in 9 results : FDA 2 Generic
  9. Teicoplanin : 2 outcomes 2 studies in 2 results : IBA
  10. clinafloxacin : 2 outcomes 2 studies in 2 results : IBA
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Diseases Related to Pneumococcal Meningitis

  1. Meningitis
  2. Infection
  3. Hearing Loss (Hearing Impairment)
  4. Inflammation
  5. Pneumonia (Pneumonitis)
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Key Therapies for Pneumococcal Meningitis

Efficacy Chart >>
  1. Cochlear Implantation : 1 outcome 2 studies in 10 results
  2. Splenectomy : 1 outcome in 13 results
  3. Catheters : 1 outcome in 2 results
  4. Intramuscular Injections : 1 outcome in 2 results
  5. Cochlear Implants (Cochlear Implant) : 1 study in 12 results
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