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Hairy Cell Leukemia Summary

Description: A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.

Also Known As: Leukemia, Hairy Cell; Hairy Cell Leukemias; Leukemias, Hairy Cell; Leukemic Reticuloendothelioses; Reticuloendothelioses, Leukemic Show All >>

Networked: 1329 relevant articles (162 outcomes, 116 trials/studies) for this Disease

Key Drugs and Agents for Hairy Cell Leukemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cladribine : 42 outcomes 15 studies in 226 results : FDA 3 Generic
  2. Interferon-alpha (Interferon Alfa) : 31 outcomes 17 studies in 197 results : FDA 2
  3. Pentostatin (Nipent) : 28 outcomes 17 studies in 111 results : FDA 2 Generic
  4. Interferons : 20 outcomes 17 studies in 156 results : IBA
  5. purine : 17 outcomes 3 studies in 68 results : IBA
  6. rituximab (Mabthera) : 11 outcomes 5 studies in 42 results : FDA 3
  7. 2-chloro-3'-deoxyadenosine : 6 outcomes 3 studies in 27 results : IBA
  8. Immunotoxins (Immunotoxin) : 4 outcomes 6 studies in 19 results : IBA
  9. Adenosine Deaminase : 4 outcomes 1 study in 18 results : IBA
  10. Granulocyte Colony-Stimulating Factor (G-CSF) : 3 outcomes in 7 results : IBA
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Diseases Related to Hairy Cell Leukemia

  1. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
  2. Residual Neoplasm
  3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
  4. Infection
  5. Splenomegaly
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Key Therapies for Hairy Cell Leukemia

Efficacy Chart >>
  1. Splenectomy : 13 outcomes 9 studies in 110 results
  2. Drug Therapy (Chemotherapy) : 8 outcomes 1 study in 32 results
  3. Aftercare (After-Treatment) : 7 outcomes 1 study in 34 results
  4. Retreatment : 2 outcomes in 3 results
  5. Transplants (Transplant) : 1 outcome 1 study in 3 results
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