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Keratins (Keratin) Summary

Description: A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

Also Known As: Keratin; Cytokeratin; Glycosylated Keratin; Keratin, Glycosylated; Keratin-Associated Proteins Show All >>

Networked: 7718 relevant articles (124 outcomes, 740 trials/studies) for this Bio-Agent

Key Diseases for which Keratins is Relevant

  1. Neoplasms (Cancer) : 42 outcomes 247 studies in 3142 results
  2. Carcinoma (Carcinomatosis) : 23 outcomes 88 studies in 959 results
  3. Adenocarcinoma : 9 outcomes 29 studies in 331 results
  4. Squamous Cell Carcinoma (Epidermoid Carcinoma) : 6 outcomes 36 studies in 379 results
  5. Seminoma : 5 outcomes 3 studies in 33 results
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Drugs Related to Keratins

  1. Antibodies
  2. Vimentin
  3. DNA (Deoxyribonucleic Acid)
  4. Mucin-1 (CA 15-3 Antigen)
  5. Antigens
  6. Carcinoembryonic Antigen
  7. Monoclonal Antibodies
  8. Proteins (Proteins, Gene)
  9. Carbon Monoxide
  10. Keratin-7 (Cytokeratin 7)
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Therapies Related to Keratins

  1. Transplants (Transplant)
  2. Neoadjuvant Therapy
  3. Decompression
  4. Drug Therapy (Chemotherapy)
  5. Lasers (Laser)
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