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Insulin (Novolin) Summary

Description: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

Also Known As: Novolin; Iletin; Humulin; Velosulin; Humulin S Show All >>

Networked: 79131 relevant articles (4165 outcomes, 9051 trials/studies) for this Drug

Key Diseases for which Insulin is Relevant

  1. Insulin Resistance : 683 outcomes 1341 studies in 15306 results
  2. Body Weight (Weight, Body) : 409 outcomes 381 studies in 5107 results
  3. Weight Loss (Weight Reduction) : 340 outcomes 194 studies in 1718 results
  4. Hyperglycemia : 319 outcomes 389 studies in 5217 results
  5. Type 2 Diabetes Mellitus (MODY) : 273 outcomes 795 studies in 5426 results
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Drugs Related to Insulin

  1. Glucose (Dextrose)
  2. Blood Glucose (Blood Sugar)
  3. Metformin (Glucophage)
  4. Adiponectin
  5. Leptin
  6. Cholesterol
  7. Glucagon (Glukagon)
  8. C-Peptide
  9. Triglycerides (Triacylglycerol)
  10. pioglitazone (Actos)
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Therapies Related to Insulin

  1. Injections
  2. Transplantation (Transplant Recipients)
  3. Oral Administration
  4. Caloric Restriction
  5. Gastric Bypass (Roux-en-Y Gastric Bypass)
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