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Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell) Summary

Description: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.

Also Known As: Histiocytosis, Langerhans Cell; Histiocytosis-X; Letterer-Siwe Disease; Langerhans-Cell Granulomatosis; Histiocytosis, Langerhans-Cell Show All >>

Networked: 922 relevant articles (44 outcomes, 64 trials/studies) for this Disease

Key Drugs and Agents for Langerhans-Cell Histiocytosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cladribine : 11 outcomes 7 studies in 37 results : FDA 3 Generic
  2. Thalidomide (Thalomid) : 3 outcomes 2 studies in 17 results : FDA 2
  3. Vinblastine (Vinblastine Sulfate) : 2 outcomes 3 studies in 26 results : FDA 7
  4. Mechlorethamine (Nitrogen Mustard) : 2 outcomes 2 studies in 15 results : FDA 1
  5. Cytarabine (Cytosar-U) : 2 outcomes 2 studies in 10 results : FDA 13 Generic
  6. purine : 2 outcomes 1 study in 3 results : IBA
  7. Prednisolone (Predate) : 2 outcomes in 11 results : FDA 55 Generic
  8. lenalidomide (CC 5013) : 2 outcomes in 3 results : FDA 2
  9. Etoposide (VP 16) : 1 outcome 4 studies in 40 results : FDA 16 Generic
  10. Peanut Agglutinin : 1 outcome 4 studies in 13 results : IBA
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Diseases Related to Langerhans-Cell Histiocytosis

  1. Juvenile Xanthogranuloma
  2. Pulmonary Hypertension (Ayerza Syndrome)
  3. Pain (Aches)
  4. Myelodysplastic Syndromes (Myelodysplastic Syndrome)
  5. Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)
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Key Therapies for Langerhans-Cell Histiocytosis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 6 outcomes 1 study in 94 results
  2. Radiotherapy : 2 outcomes 2 studies in 26 results
  3. Salvage Therapy : 1 outcome 1 study in 7 results
  4. Hematopoietic Stem Cell Transplantation : 1 outcome 1 study in 5 results
  5. Stem Cell Transplantation : 1 outcome in 8 results
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