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Hirschsprung Disease (Hirschsprung's Disease) Summary

Description: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.

Also Known As: Hirschsprung's Disease; Congenital Megacolon; Aganglionosis, Rectosigmoid Colon; Aganglionosis, Total Colonic; Rectosigmoid Aganglionosis Show All >>

Networked: 1212 relevant articles (20 outcomes, 117 trials/studies) for this Disease

Key Drugs and Agents for Hirschsprung Disease

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Acetylcholinesterase : 6 outcomes 5 studies in 105 results : IBA
  2. calretinin : 2 outcomes 5 studies in 25 results : IBA
  3. Anorectal atresia : 1 outcome 5 studies in 64 results : IBA
  4. Eosine Yellowish-(YS) (Eosin) : 1 outcome 1 study in 16 results : IBA
  5. Hematoxylin (Haematoxylon) : 1 outcome 1 study in 11 results : IBA
  6. Neurotransmitter Agents (Neurotransmitter) : 1 outcome 1 study in 5 results : IBA
  7. Tea : 1 outcome 1 study in 1 result : IBA
  8. Currarino triad : 1 outcome in 7 results : IBA
  9. Polyethylene Glycols (Polyethylene Glycol) : 1 outcome in 2 results : FDA 36 Generic
  10. Potassium : 1 outcome in 1 result : IBA
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Diseases Related to Hirschsprung Disease

  1. Enterocolitis
  2. Ganglion Cysts (Ganglion)
  3. Sepsis (Septicemia)
  4. Meningitis
  5. Constipation
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Key Therapies for Hirschsprung Disease

Efficacy Chart >>
  1. Colostomy : 3 outcomes 3 studies in 76 results
  2. Enema (Enemas) : 1 outcome 10 studies in 67 results
  3. Tissue Therapy (Cell Therapy) : 1 outcome 3 studies in 5 results
  4. Colectomy : 1 outcome 2 studies in 26 results
  5. Transplantation (Transplant Recipients) : 1 outcome 1 study in 13 results
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