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Multiple Hamartoma Syndrome (Cowden's Disease) Summary

Description: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.

Also Known As: Cowden's Disease; Cowdens Disease; Hamartoma Syndrome, Multiple; Bannayan-Zonana Syndrome; Cowden Syndrome Show All >>

Networked: 185 relevant articles (1 outcomes, 8 trials/studies) for this Disease

Key Drugs and Agents for Multiple Hamartoma Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Etretinate : 1 outcome in 1 result : FDA 1
  2. PTEN Phosphohydrolase (PTEN Phosphatase) : 2 studies in 14 results : IBA
  3. Sirolimus (Rapamycin) : 1 study in 4 results : FDA 2
  4. Proteins (Proteins, Gene) : 1 study in 3 results : IBA
  5. Turcot syndrome : 1 study in 3 results : IBA
  6. Epidermal Growth Factor (EGF) : 1 study in 1 result : IBA
  7. Barium : 1 study in 1 result : IBA
  8. Hereditary renal agenesis : 1 study in 1 result : IBA
  9. tensins (tensin) : 51 results : IBA
  10. Juvenile polyposis syndrome : 19 results : IBA
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Diseases Related to Multiple Hamartoma Syndrome

  1. Neoplasms (Cancer)
  2. Multiple Hamartoma Syndrome (Cowden's Disease)
  3. Neurofibromatosis 1 (Neurofibromatosis Type I)
  4. Tuberous Sclerosis (Bourneville's Disease)
  5. Basal Cell Nevus Syndrome (Gorlin Syndrome)
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Key Therapies for Multiple Hamartoma Syndrome

Efficacy Chart >>
  1. Enema (Enemas) : 1 study in 1 result
  2. Thyroidectomy : 5 results
  3. Gas Lasers : 2 results
  4. Simple Mastectomy : 2 results
  5. Airway Management : 1 result
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