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Glucosylceramidase (Glucocerebrosidase) Summary

Description: A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.

Also Known As: Glucocerebrosidase; Acid beta-Glucosidase; Glucosylceramide beta-Glucosidase; Glucocerebroside beta-Glucosidase; Glucosyl Ceramidase Show All >>

Networked: 1049 relevant articles (23 outcomes, 70 trials/studies) for this Bio-Agent

Key Diseases for which Glucosylceramidase is Relevant

  1. Gaucher Disease (Gaucher's Disease) : 20 outcomes 52 studies in 902 results
  2. Neurologic Manifestations (Neurological Manifestations) : 2 outcomes in 9 results
  3. Lysosomal Storage Diseases (Lysosomal Storage Disease) : 1 outcome 1 study in 61 results
  4. Thrombocytopenia (Thrombopenia) : 1 outcome in 6 results
  5. Splenomegaly : 1 outcome in 3 results
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Drugs Related to Glucosylceramidase

  1. Mannose (D-Mannose)
  2. imiglucerase (Cerezyme)
  3. alglucerase (Ceredase)
  4. Lysergic Acid Diethylamide (LSD)
  5. Glucosylceramidase (Glucocerebrosidase)
  6. Complementary DNA (cDNA)
  7. Glucose (Dextrose)
  8. Synucleins
  9. DNA (Deoxyribonucleic Acid)
  10. conduritol epoxide
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Therapies Related to Glucosylceramidase

  1. Enzyme Replacement Therapy
  2. Enzyme Therapy
  3. Intravenous Infusions
  4. Complementary Therapies (Alternative Medicine)
  5. Therapeutics
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