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Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase) Summary

Description: An enzyme that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate, and is a part of the glycolytic and gluconeogenic pathways. Deficiency of the enzyme, an autosomal recessive trait, results in liver glycogenesis and hemolytic anemia. EC 5.3.1.9.

Also Known As: Phosphoglucose Isomerase; Glucose 6 Phosphate Isomerase; Glucosephosphate Isomerase; Isomerase, Glucose 6 Phosphate; Isomerase, Glucose-6-Phosphate Show All >>

Networked: 267 relevant articles (8 outcomes, 20 trials/studies) for this Bio-Agent

Key Diseases for which Glucose-6-Phosphate Isomerase is Relevant

  1. Arthritis (Polyarthritis) : 3 outcomes 3 studies in 48 results
  2. Neoplasms (Cancer) : 1 outcome 5 studies in 58 results
  3. Carcinoma (Carcinomatosis) : 1 outcome 3 studies in 22 results
  4. Hemolytic Anemia : 1 outcome in 15 results
  5. Breast Neoplasms (Breast Cancer) : 1 outcome in 12 results
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Drugs Related to Glucose-6-Phosphate Isomerase

  1. Enzymes
  2. L-Lactate Dehydrogenase (Lactate Dehydrogenase)
  3. Hexokinase
  4. 4- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)
  5. imatinib (Gleevec)
  6. Alanine Transaminase (SGPT)
  7. Phosphoglycerate Kinase (Kinase, Phosphoglycerate)
  8. Triose-Phosphate Isomerase (Triosephosphate Isomerase)
  9. fingolimod (FTY720)
  10. Transketolase
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Therapies Related to Glucose-6-Phosphate Isomerase

  1. Drug Therapy (Chemotherapy)
  2. Radiotherapy
  3. Adjuvant Chemotherapy
  4. Mastectomy (Mammectomy)

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