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Fissure in Ano (Anal Fissure) Summary

Description: A painful linear ulcer at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal. (Dorland, 27th ed & Stedman, 25th ed)

Also Known As: Anal Fissure; Anal Ulcers; Fissure, Anal; Ulcer, Anal; Ulcers, Anal Show All >>

Networked: 404 relevant articles (80 outcomes, 112 trials/studies) for this Disease

Key Drugs and Agents for Fissure in Ano

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Botulinum Toxins (Botulinum Toxin) : 32 outcomes 30 studies in 124 results : IBA
  2. Nitroglycerin (Dynamite) : 25 outcomes 40 studies in 118 results : FDA 53 Generic
  3. Diltiazem (Cardizem) : 11 outcomes 14 studies in 37 results : FDA 50 Generic
  4. Nifedipine (Adalat) : 6 outcomes 8 studies in 21 results : FDA 25 Generic
  5. Isosorbide Dinitrate (Isordil) : 3 outcomes 7 studies in 18 results : FDA 43 Generic
  6. Lidocaine (Xylocaine) : 3 outcomes 7 studies in 12 results : FDA 168 Generic
  7. onabotulinumtoxinA (Botox) : 3 outcomes 3 studies in 12 results : FDA 1
  8. Calcium Channel Blockers (Blockers, Calcium Channel) : 2 outcomes in 5 results : IBA
  9. Glycerol (Glycerine) : 1 outcome 3 studies in 6 results : FDA 6 Generic
  10. Hydrocortisone (Cortisol) : 1 outcome 2 studies in 3 results : FDA 176 Generic
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Diseases Related to Fissure in Ano

  1. Pain (Aches)
  2. Headache (Headaches)
  3. Hemorrhoids
  4. Esophageal Achalasia (Megaesophagus)
  5. Constipation
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Key Therapies for Fissure in Ano

Efficacy Chart >>
  1. Local Anesthesia : 1 outcome 3 studies in 7 results
  2. Injections : 1 outcome 1 study in 17 results
  3. Lasers (Laser) : 1 outcome 1 study in 3 results
  4. Transcutaneous Electric Nerve Stimulation (TENS) : 1 outcome in 2 results
  5. Moxibustion : 1 outcome in 1 result
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