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Absence Epilepsy (Absence Seizure) Summary

Description: A childhood seizure disorder characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Also Known As: Absence Seizure; Childhood Absence Epilepsy; Absence Seizures; Epilepsy, Juvenile Absence; Seizure, Absence Show All >>

Networked: 1001 relevant articles (86 outcomes, 139 trials/studies) for this Disease

Key Drugs and Agents for Absence Epilepsy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. lamotrigine (Lamictal) : 17 outcomes 14 studies in 57 results : FDA 33 Generic
  2. Valproic Acid (Valproate, Semisodium) : 16 outcomes 15 studies in 119 results : FDA 51 Generic
  3. Ethosuximide (Zarontin) : 11 outcomes 10 studies in 121 results : FDA 7 Generic
  4. Anticonvulsants (Antiepileptic Drugs) : 11 outcomes 5 studies in 54 results : IBA
  5. Lennox-Gastaut type Epileptic encephalopathy : 8 outcomes 7 studies in 45 results : IBA
  6. Pentylenetetrazole (Metrazol) : 5 outcomes 3 studies in 30 results : IBA
  7. Phenytoin (Dilantin) : 5 outcomes 2 studies in 18 results : FDA 9 Generic
  8. zonisamide (Zonegran) : 5 outcomes 2 studies in 11 results : FDA 19 Generic
  9. gamma-Aminobutyric Acid (GABA) : 4 outcomes 14 studies in 99 results : IBA
  10. Carbamazepine (Tegretol) : 4 outcomes 3 studies in 31 results : FDA 24 Generic
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Diseases Related to Absence Epilepsy

  1. Seizures (Seizure)
  2. Epilepsy (Aura)
  3. Absence Epilepsy (Absence Seizure)
  4. Generalized Epilepsy
  5. Myoclonic Epilepsies (Myoclonic Encephalopathy)
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Key Therapies for Absence Epilepsy

Efficacy Chart >>
  1. Injections : 2 outcomes 2 studies in 15 results
  2. Ketogenic Diet : 2 outcomes 1 study in 7 results
  3. Vagus Nerve Stimulation : 2 outcomes 1 study in 3 results
  4. Withholding Treatment : 1 outcome in 2 results
  5. Carbohydrate-Restricted Diet (Low Carbohydrate Diet) : 1 outcome in 1 result
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