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Toxic Epidermal Necrolysis
(Lyell's Syndrome)
Summary
Description:
An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure.
Also Known As:
Lyell's Syndrome; Epidermal Necrolysis, Toxic; Nonstaphylococcal Scalded Skin Syndrome; Epidermal Necrolyses, Toxic; Lyell Syndrome Show All >>
Networked: 1143
relevant articles (34 outcomes,
54 trials/studies)
for this Disease
Key Drugs and Agents for Toxic Epidermal Necrolysis
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
-
Immunoglobulins (Immunoglobulin)
:
11 outcomes 6 studies in 81 results
: IBA
-
Intravenous Immunoglobulins (IVIG)
:
6 outcomes 4 studies in 43 results
:
FDA 1
-
Adrenal Cortex Hormones (Corticosteroids)
:
2 outcomes in 22 results
: IBA
-
Antibodies
:
2 outcomes in 6 results
: IBA
-
Cyclophosphamide (Cytoxan)
:
2 outcomes in 4 results
:
FDA 10
Generic
-
Anticonvulsants (Antiepileptic Drugs)
:
1 outcome 4 studies in 41 results
: IBA
-
Phenytoin (Dilantin)
:
1 outcome 3 studies in 44 results
:
FDA 9
Generic
-
lamotrigine (Lamictal)
:
1 outcome 1 study in 48 results
:
FDA 33
Generic
-
Anti-Bacterial Agents (Antibiotics)
:
1 outcome 1 study in 21 results
: IBA
-
Carboxymethylcellulose Sodium (Polycell)
:
1 outcome 1 study in 4 results
:
FDA 2
Show All >>
Diseases Related to Toxic Epidermal Necrolysis
-
Stevens-Johnson Syndrome
-
Graft vs Host Disease (Graft-Versus-Host Disease)
-
Burns
-
Skin Diseases
-
Urticaria (Hives)
Show All >>
Key Therapies for Toxic Epidermal Necrolysis
Efficacy Chart >>
-
Plasmapheresis
:
5 outcomes 3 studies in 18 results
-
Plasma Exchange
:
2 outcomes in 9 results
-
Radiotherapy
:
1 outcome in 21 results
-
Transplantation (Transplant Recipients)
:
1 outcome in 12 results
-
Hemoperfusion
:
1 outcome in 5 results
Show All >>
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