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De Lange Syndrome (Cornelia De Lange Syndrome) Summary

Description: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)

Also Known As: Cornelia De Lange Syndrome; De Lange's Syndrome; Typus Degenerativus Amstelodamensis; Amstelodamensis, Typus Degenerativus; Brachmann De Lange Syndrome Show All >>

Networked: 108 relevant articles (0 outcomes, 2 trials/studies) for this Disease

Key Drugs and Agents for De Lange Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Proteins (Proteins, Gene) : 1 study in 10 results : IBA
  2. chenodeoxycholate sulfate conjugate (CDCS) : 1 study in 1 result : IBA
  3. cohesins (cohesin) : 37 results : IBA
  4. Roberts Syndrome : 9 results : IBA
  5. Staphylococcal Protein A (A, Protein) : 5 results : IBA
  6. Congenital diaphragmatic hernia : 4 results : IBA
  7. Fryns syndrome : 3 results : IBA
  8. Jarcho-Levin syndrome : 3 results : IBA
  9. Cohen syndrome : 3 results : IBA
  10. Pregnancy-Associated Plasma Protein-A (PAPP-A) : 2 results : IBA
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Diseases Related to De Lange Syndrome

  1. Cri-du-Chat Syndrome (5p- Syndrome)
  2. CHARGE Syndrome
  3. Mental Retardation (Idiocy)
  4. Sotos Syndrome
  5. Rubinstein-Taybi Syndrome (Syndrome, Rubinstein-Taybi)
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Key Therapies for De Lange Syndrome

Efficacy Chart >>
  1. General Anesthesia : 3 results
  2. Orchiopexy : 2 results
  3. Anesthesia : 2 results
  4. Airway Management : 1 result
  5. Catheters : 1 result
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