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Cushing Syndrome
Summary
Description:
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Also Known As:
Cushing's Syndrome; Syndrome, Cushing's; Syndrome, Cushing; Hypercortisolism
Networked: 4565
relevant articles (264 outcomes,
298 trials/studies)
for this Disease
Key Drugs and Agents for Cushing Syndrome
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
-
Adrenocorticotropic Hormone (ACTH)
:
68 outcomes 72 studies in 1571 results
:
FDA 7
-
Hydrocortisone (Cortisol)
:
54 outcomes 78 studies in 1200 results
:
FDA 176
Generic
-
Dexamethasone (Maxidex)
:
24 outcomes 33 studies in 413 results
:
FDA 77
Generic
-
Ketoconazole (Nizoral)
:
14 outcomes 6 studies in 77 results
:
FDA 20
Generic
-
Mifepristone (RU 486)
:
10 outcomes 10 studies in 59 results
:
FDA 1
-
Metyrapone
:
10 outcomes 4 studies in 82 results
:
FDA 1
-
Mitotane (Lysodren)
:
8 outcomes 3 studies in 54 results
:
FDA 1
-
Corticotropin-Releasing Hormone
:
6 outcomes 7 studies in 115 results
: IBA
-
Glucose (Dextrose)
:
6 outcomes 4 studies in 82 results
:
FDA 175
Generic
-
Deamino Arginine Vasopressin (Desmopressin)
:
5 outcomes 4 studies in 34 results
:
FDA 16
Generic
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Diseases Related to Cushing Syndrome
-
Cushing Syndrome
-
Neoplasms (Cancer)
-
Adenoma (Adenomas)
-
Hypertension (High Blood Pressure)
-
Pheochromocytoma
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Key Therapies for Cushing Syndrome
Efficacy Chart >>
-
Adrenalectomy
:
49 outcomes 25 studies in 559 results
-
Hypophysectomy
:
7 outcomes 2 studies in 42 results
-
Radiotherapy
:
6 outcomes 1 study in 24 results
-
Aftercare (After-Treatment)
:
4 outcomes 2 studies in 50 results
-
Pituitary Irradiation
:
4 outcomes 1 study in 14 results
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