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Crohn Disease (Crohn's Disease) Summary

Description: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

Also Known As: Crohn's Disease; Crohns Disease; Colitis, Granulomatous; Enteritis, Granulomatous; Enteritis, Regional Show All >>

Networked: 12139 relevant articles (1624 outcomes, 1678 trials/studies) for this Disease

Key Drugs and Agents for Crohn Disease

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. infliximab (Remicade) : 363 outcomes 218 studies in 1562 results : FDA 2
  2. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 144 outcomes 82 studies in 923 results : IBA
  3. adalimumab (Humira) : 129 outcomes 85 studies in 460 results : FDA 2
  4. Azathioprine (Imuran) : 129 outcomes 81 studies in 593 results : FDA 7 Generic
  5. Adrenal Cortex Hormones (Corticosteroids) : 93 outcomes 28 studies in 288 results : IBA
  6. Mesalamine (Mesalazine) : 90 outcomes 68 studies in 320 results : FDA 10 Generic
  7. Methotrexate (Mexate) : 67 outcomes 36 studies in 203 results : FDA 8 Generic
  8. 6-Mercaptopurine (Mercaptopurine) : 64 outcomes 33 studies in 222 results : FDA 4 Generic
  9. Budesonide (Pulmicort) : 58 outcomes 37 studies in 158 results : FDA 10 Generic
  10. Steroids : 44 outcomes 24 studies in 214 results : IBA
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Diseases Related to Crohn Disease

  1. Ulcerative Colitis
  2. Rheumatoid Arthritis
  3. Fistula
  4. Necrosis
  5. Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
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Key Therapies for Crohn Disease

Efficacy Chart >>
  1. Enteral Nutrition (Feeding, Tube) : 87 outcomes 36 studies in 269 results
  2. Remission Induction : 40 outcomes 20 studies in 93 results
  3. Biological Therapy : 23 outcomes 20 studies in 154 results
  4. Drug Therapy (Chemotherapy) : 14 outcomes 15 studies in 95 results
  5. Total Parenteral Nutrition : 12 outcomes 8 studies in 91 results
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