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Cocaine (Cocaine HCl) Summary

Description: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Also Known As: Cocaine HCl; Cocaine Hydrochloride; HCl, Cocaine; Hydrochloride, Cocaine; 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-

Networked: 6739 relevant articles (215 outcomes, 887 trials/studies) for this Bio-Agent

Key Diseases for which Cocaine is Relevant

  1. Cocaine-Related Disorders (Cocaine Addiction) : 59 outcomes 204 studies in 1064 results
  2. Substance-Related Disorders (Drug Abuse) : 26 outcomes 150 studies in 860 results
  3. Seizures (Seizure) : 21 outcomes 66 studies in 402 results
  4. Lacerations : 6 outcomes 4 studies in 38 results
  5. Chest Pain (Chest Pains) : 5 outcomes 25 studies in 168 results
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Drugs Related to Cocaine

  1. Epinephrine (Adrenaline)
  2. Nicotine
  3. Tetracaine (Amethocaine)
  4. Methadone (Dolophine)
  5. Heroin (Diamorphine)
  6. Amphetamine (Amfetamine)
  7. Ethanol (Ethyl Alcohol)
  8. Diazepam (Valium)
  9. Methamphetamine (Desoxyn)
  10. N-Methylaspartate (NMDA)
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Therapies Related to Cocaine

  1. Self Administration (Administration, Self)
  2. Drug Therapy (Chemotherapy)
  3. Anesthesia
  4. Injections
  5. Prenatal Care
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