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Hemophilia B (Haemophilia B) Summary

Description: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

Also Known As: Haemophilia B; Christmas Disease; Factor IX Deficiency; Deficiency, Factor IX; B, Haemophilia Show All >>

Networked: 1260 relevant articles (54 outcomes, 144 trials/studies) for this Disease

Key Drugs and Agents for Hemophilia B

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Factor IX (PTC) : 33 outcomes 93 studies in 822 results : FDA 2 Generic
  2. prothrombin complex concentrates (PPSB) : 6 outcomes 11 studies in 67 results : IBA
  3. Antigens : 4 outcomes 6 studies in 77 results : IBA
  4. Factor VIII (Coagulation Factor VIII) : 3 outcomes 12 studies in 110 results : IBA
  5. Complementary DNA (cDNA) : 3 outcomes 5 studies in 22 results : IBA
  6. Mononine : 1 outcome 4 studies in 8 results : IBA
  7. Antibodies : 1 outcome 3 studies in 60 results : IBA
  8. recombinant FVIIa (rFVIIa) : 1 outcome 2 studies in 28 results : IBA
  9. Tranexamic Acid (AMCA) : 1 outcome 2 studies in 6 results : FDA 3
  10. 6-Aminocaproic Acid (6 Aminocaproic Acid) : 1 outcome 2 studies in 4 results : FDA 3 Generic
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Diseases Related to Hemophilia B

  1. Hemorrhage
  2. Hemophilia A (Haemophilia)
  3. Body Weight (Weight, Body)
  4. Hepatitis
  5. Disease Susceptibility (Diathesis)
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Key Therapies for Hemophilia B

Efficacy Chart >>
  1. Intramuscular Injections : 3 outcomes 7 studies in 16 results
  2. Transplantation (Transplant Recipients) : 1 outcome 3 studies in 4 results
  3. Tissue Therapy (Cell Therapy) : 1 outcome 1 study in 2 results
  4. Intravenous Infusions : 3 studies in 12 results
  5. Aftercare (After-Treatment) : 1 study in 3 results
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