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Cathepsin B Summary

Description: A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.

Also Known As: Cathepsin B-Like Proteinase; Cathepsin B1; Cathepsin B Like Proteinase; Proteinase, Cathepsin B-Like

Networked: 1228 relevant articles (16 outcomes, 174 trials/studies) for this Bio-Agent

Key Diseases for which Cathepsin B is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 44 studies in 431 results
  2. Carcinoma (Carcinomatosis) : 2 outcomes 12 studies in 89 results
  3. Pancreatitis : 2 outcomes 6 studies in 52 results
  4. Wounds and Injuries (Trauma) : 2 outcomes in 14 results
  5. Edema : 2 outcomes in 8 results
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Drugs Related to Cathepsin B

  1. Caerulein (Ceruletide)
  2. Protease Inhibitors (Protease Inhibitor)
  3. Malate Dehydrogenase (Dehydrogenase, Malate)
  4. Amylases
  5. Laminin (Merosin)
  6. Cystatin C
  7. Amyloid Precursor Protein Secretases (beta-Secretase)
  8. Galactosamine
  9. Amyloid (Amyloid Fibrils)
  10. Leukocyte Elastase (Neutrophil Elastase)
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Therapies Related to Cathepsin B

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Therapeutics
  4. Ligation
  5. Intraperitoneal Injections
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