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Caffeine (No Doz) Summary

Description: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

Also Known As: No Doz; Vivarin; 1,3,7-Trimethylxanthine; Berlin-Chemie Brand of Caffeine; Bristol-Myers Squibb Brand of Caffeine Show All >>

Networked: 5076 relevant articles (316 outcomes, 781 trials/studies) for this Drug

Key Diseases for which Caffeine is Relevant

  1. Migraine Disorders (Migraine) : 27 outcomes 29 studies in 129 results
  2. Pain (Aches) : 22 outcomes 42 studies in 157 results
  3. Contracture : 21 outcomes 42 studies in 718 results
  4. Apnea : 17 outcomes 32 studies in 183 results
  5. Body Weight (Weight, Body) : 13 outcomes 34 studies in 290 results
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Drugs Related to Caffeine

  1. Acetaminophen (Paracetamol)
  2. Aspirin (Acetylsalicylic Acid)
  3. Ergotamine (Ergotamine Tartrate)
  4. Sumatriptan (Imigran)
  5. Coffee
  6. Ephedrine
  7. Halothane (Fluothane)
  8. Ibuprofen (Motrin)
  9. Indomethacin (Indometacin)
  10. Prochlorperazine (Compazine)
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Therapies Related to Caffeine

  1. Drug Therapy (Chemotherapy)
  2. Bed Rest (Bedrest)
  3. Oral Administration
  4. Aftercare (After-Treatment)
  5. Intravenous Infusions
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