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Burkitt Lymphoma (Burkitt's Lymphoma) Summary

Description: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.

Also Known As: Burkitt's Lymphoma; Burkitt's Leukemia; Burkitts Lymphoma; Lymphoma, Burkitt's; Burkitt Leukemia Show All >>

Networked: 2800 relevant articles (105 outcomes, 208 trials/studies) for this Disease

Key Drugs and Agents for Burkitt Lymphoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. rituximab (Mabthera) : 15 outcomes 13 studies in 78 results : FDA 3
  2. Cyclophosphamide (Cytoxan) : 9 outcomes 3 studies in 59 results : FDA 10 Generic
  3. Methotrexate (Mexate) : 8 outcomes 3 studies in 42 results : FDA 8 Generic
  4. Vincristine (Oncovin) : 6 outcomes 1 study in 37 results : FDA 17 Generic
  5. Doxorubicin (Adriamycin) : 5 outcomes 3 studies in 29 results : FDA 12 Generic
  6. Cytarabine (Cytosar-U) : 4 outcomes 2 studies in 30 results : FDA 13 Generic
  7. Nasopharyngeal carcinoma : 3 outcomes 10 studies in 292 results : IBA
  8. Etoposide (VP 16) : 3 outcomes 4 studies in 21 results : FDA 16 Generic
  9. Antibodies : 3 outcomes 2 studies in 80 results : IBA
  10. Antigens : 2 outcomes 11 studies in 229 results : IBA
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Diseases Related to Burkitt Lymphoma

  1. Leukemia
  2. Lymphoma (Lymphomas)
  3. Neoplasms (Cancer)
  4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
  5. Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
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Key Therapies for Burkitt Lymphoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 54 outcomes 21 studies in 253 results
  2. Combination Drug Therapy (Combination Chemotherapy) : 7 outcomes 2 studies in 26 results
  3. Heterologous Transplantation (Xenotransplantation) : 3 outcomes 5 studies in 32 results
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 3 outcomes 1 study in 19 results
  5. Highly Active Antiretroviral Therapy (HAART) : 3 outcomes in 17 results
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