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Blast Crisis
(Blast Phase)
Summary
Description:
An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
Also Known As:
Blast Phase; Blast Crises; Blast Phases; Crises, Blast; Crisis, Blast Show All >>
Networked: 1213
relevant articles (110 outcomes,
116 trials/studies)
for this Disease
Key Drugs and Agents for Blast Crisis
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
-
imatinib (Gleevec)
:
39 outcomes 28 studies in 285 results
:
FDA 3
-
dasatinib (BMS 354825)
:
8 outcomes 7 studies in 47 results
:
FDA 2
-
Cytarabine (Cytosar-U)
:
7 outcomes 12 studies in 61 results
:
FDA 13
Generic
-
Interferon-alpha (Interferon Alfa)
:
5 outcomes 2 studies in 16 results
:
FDA 2
-
Hydroxyurea (Hydrea)
:
5 outcomes 1 study in 26 results
:
FDA 6
Generic
-
Protein-Tyrosine Kinases (Tyrosine Kinase)
:
5 outcomes in 53 results
: IBA
-
Vincristine (Oncovin)
:
5 outcomes in 31 results
:
FDA 17
Generic
-
Busulfan (Busulfex)
:
4 outcomes 2 studies in 20 results
:
FDA 2
-
Prednisone (Sone)
:
4 outcomes 2 studies in 14 results
:
FDA 119
Generic
-
4- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)
:
3 outcomes 4 studies in 23 results
:
FDA 1
Show All >>
Diseases Related to Blast Crisis
-
BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
-
Leukemia
-
Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
-
Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
-
Philadelphia Chromosome
Show All >>
Key Therapies for Blast Crisis
Efficacy Chart >>
-
Drug Therapy (Chemotherapy)
:
16 outcomes 2 studies in 79 results
-
Transplants (Transplant)
:
5 outcomes 2 studies in 38 results
-
Transplantation (Transplant Recipients)
:
4 outcomes 1 study in 34 results
-
Bone Marrow Transplantation (Transplantation, Bone Marrow)
:
4 outcomes 1 study in 30 results
-
Stem Cell Transplantation
:
3 outcomes in 22 results
Show All >>
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