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Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis) Summary

Description: Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (Still's Disease, Juvenile-Onset), polyarticular-onset, and pauciarticular-onset. Adult-onset cases of Still's disease (STILL'S DISEASE, ADULT-ONSET) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.

Also Known As: Juvenile Idiopathic Arthritis; Juvenile Chronic Arthritis; Arthritis, Juvenile Rheumatoid; Juvenile-Onset Still Disease; Juvenile-Onset Stills Disease Show All >>

Networked: 2763 relevant articles (238 outcomes, 344 trials/studies) for this Disease

Key Drugs and Agents for Juvenile Rheumatoid Arthritis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. TNFR-Fc fusion protein (etanercept) : 43 outcomes 26 studies in 195 results : FDA 2
  2. Methotrexate (Mexate) : 42 outcomes 26 studies in 240 results : FDA 8 Generic
  3. tocilizumab : 20 outcomes 19 studies in 73 results : FDA 2
  4. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 13 outcomes 13 studies in 135 results : IBA
  5. Interleukin-6 (Interleukin 6) : 10 outcomes 11 studies in 84 results : IBA
  6. Interleukin 1 Receptor Antagonist Protein (Anakinra) : 10 outcomes 3 studies in 28 results : FDA 2
  7. adalimumab (Humira) : 7 outcomes 8 studies in 52 results : FDA 2
  8. infliximab (Remicade) : 7 outcomes 7 studies in 61 results : FDA 2
  9. Interleukin-1 (Interleukin 1) : 6 outcomes 5 studies in 42 results : IBA
  10. Amyopathic dermatomyositis : 5 outcomes 7 studies in 54 results : IBA
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Diseases Related to Juvenile Rheumatoid Arthritis

  1. Rheumatoid Arthritis
  2. Uveitis
  3. Arthritis (Polyarthritis)
  4. Giant Lymph Node Hyperplasia (Castleman's Disease)
  5. Systemic Lupus Erythematosus (Libman-Sacks Disease)
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Key Therapies for Juvenile Rheumatoid Arthritis

Efficacy Chart >>
  1. Injections : 6 outcomes 6 studies in 46 results
  2. Arthroplasty : 5 outcomes 5 studies in 52 results
  3. Biological Therapy : 3 outcomes in 23 results
  4. Drug Therapy (Chemotherapy) : 2 outcomes 3 studies in 30 results
  5. Stem Cell Transplantation : 2 outcomes 1 study in 29 results
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