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Eflornithine (Ornidyl) Summary

Description: An inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.

Also Known As: Ornidyl; Vaniqa; Difluoromethylornithine; DL-alpha-Difluoromethylornithine; Eflornithine Hydrochloride; Eflornithine Monohydrochloride, Monohydrate; MDL-71,782 A; RMI 71782; Women First Brand of Eflornithine Hydrochloride; alpha-Difluoromethyl Ornithine; 71782, RMI; DL alpha Difluoromethylornithine; Hydrochloride, Eflornithine; MDL 71,782 A; MDL71,782 A; Monohydrochloride, Monohydrate Eflornithine; Ornithine, alpha-Difluoromethyl; alpha Difluoromethyl Ornithine; alpha Difluoromethylornithine; alpha-Difluoromethylornithine; Ornithine, 2-(difluoromethyl)-

Networked: 718 relevant articles (43 outcomes, 96 trials/studies) for this Drug

Key Diseases for which Eflornithine is Relevant

  1. Neoplasms (Cancer) : 8 outcomes 18 studies in 188 results
  2. African Trypanosomiasis (Nagana) : 7 outcomes 6 studies in 52 results
  3. Trypanosomiasis : 4 outcomes 4 studies in 37 results
  4. Adenocarcinoma : 3 outcomes 5 studies in 24 results
  5. Infection : 3 outcomes 1 study in 33 results
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Drugs Related to Eflornithine

  1. Ornithine Decarboxylase (Decarboxylase, Ornithine)
  2. Eflornithine (Ornidyl)
  3. Nifurtimox
  4. Mitoguazone (MGBG)
  5. Piroxicam (Feldene)
  6. Aspirin (Acetylsalicylic Acid)
  7. Bleomycin (Blenoxane)
  8. Suramin (Suramin Sodium)
  9. melarsen oxide
  10. Putrescine
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Therapies Related to Eflornithine

  1. Oral Administration
  2. Heterologous Transplantation (Xenotransplantation)
  3. Chemoprevention
  4. Drug Therapy (Chemotherapy)
  5. Lasers (Laser)
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