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ZD4054 Summary

Description: a potent endothelin receptor A antagonist that inhibits ovarian carcinoma cell proliferation

Also Known As: trans,trans-2(4-methoxyphenyl)-4-(1-3-benzodiazol-5-yl)-1-(dibutylaminocarbonylmethyl)pyrrolidine-3-carboxylic acid; zibotentan

Networked: 39 relevant articles (12 outcomes, 18 trials/studies) for this Bio-Agent

Key Diseases for which ZD4054 is Relevant

  1. Prostatic Neoplasms (Prostate Cancer) : 3 outcomes 13 studies in 22 results
  2. Neoplasms (Cancer) : 3 outcomes 2 studies in 9 results
  3. Colorectal Neoplasms (Colorectal Cancer) : 3 outcomes 1 study in 3 results
  4. Ovarian Neoplasms (Ovarian Cancer) : 2 outcomes 1 study in 4 results
  5. Carcinoma (Carcinomatosis) : 2 outcomes 1 study in 3 results
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Drugs Related to ZD4054

  1. ZD4054
  2. Endothelin A Receptor
  3. Paclitaxel (Taxol)
  4. Platinum
  5. Endothelins (Endothelin)
  6. Pain-Free
  7. Hormones
  8. Carboplatin (JM8)
  9. gefitinib (Iressa)
  10. fulvestrant (Faslodex)
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Therapies Related to ZD4054

  1. Heterologous Transplantation (Xenotransplantation)
  2. Castration
  3. Drug Therapy (Chemotherapy)
  4. Stents

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