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dasatinib (BMS 354825) Summary

Description: antineoplastic; an ABL kinase inhibitor that counters resistance to imatinib; structure in first source

Also Known As: BMS 354825; (18F)-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide; BMS-354825; BMS354825; N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide Show All >>

Networked: 966 relevant articles (124 outcomes, 183 trials/studies) for this Drug

Key Diseases for which dasatinib is Relevant

  1. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) : 54 outcomes 50 studies in 410 results
  2. Philadelphia Chromosome : 23 outcomes 17 studies in 136 results
  3. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) : 19 outcomes 14 studies in 107 results
  4. Neoplasms (Cancer) : 14 outcomes 41 studies in 182 results
  5. Leukemia : 10 outcomes 12 studies in 89 results
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Drugs Related to dasatinib

  1. imatinib (Gleevec)
  2. 4- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)
  3. Protein-Tyrosine Kinases (Tyrosine Kinase)
  4. dasatinib (BMS 354825)
  5. Phosphotransferases (Kinase)
  6. src-Family Kinases
  7. Epidermal Growth Factor Receptor (EGF Receptor)
  8. bortezomib (Velcade)
  9. Adenosine Triphosphate (ATP)
  10. docetaxel (Taxotere)
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Therapies Related to dasatinib

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Castration
  4. Stem Cell Transplantation
  5. Transplantation (Transplant Recipients)
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