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Bcr-Abl tyrosine kinase Summary

Description: mutation may be the causative molecular abnormality in chronic myeloid leukemia

Key Diseases for which Bcr-Abl tyrosine kinase is Relevant

  1. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) : 31 outcomes 8 studies in 259 results
  2. Philadelphia Chromosome : 10 outcomes 2 studies in 68 results
  3. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) : 5 outcomes in 20 results
  4. Leukemia : 4 outcomes in 50 results
  5. Blast Crisis (Blast Phase) : 2 outcomes 2 studies in 12 results
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Drugs Related to Bcr-Abl tyrosine kinase

  1. imatinib (Gleevec)
  2. Phosphotransferases (Kinase)
  3. 4- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)
  4. Protein-Tyrosine Kinases (Tyrosine Kinase)
  5. dasatinib (BMS 354825)
  6. Telomerase (Telomerase Reverse Transcriptase)
  7. Interferon Type I
  8. gefitinib (Iressa)
  9. aurora kinase (aurora A kinase)
  10. Proteins (Proteins, Gene)
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Therapies Related to Bcr-Abl tyrosine kinase

  1. Stem Cell Transplantation
  2. Molecular Targeted Therapy
  3. Therapeutics

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