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aurora kinase (aurora A kinase) Summary

Description: highly conserved in eukaryotes and involved in many processes during cell division; Aurora A regulates centrosome function during M phase; Aurora-B plays roles in spindle dynamics, chromosome condensation, and cytokinesis

Also Known As: aurora A kinase; Serine/threonine-protein kinase 13; aurora B kinase; serine/threonine protein kinase 12; AIK3 protein kinase Show All >>

Networked: 684 relevant articles (34 outcomes, 113 trials/studies) for this Bio-Agent

Key Diseases for which aurora kinase is Relevant

  1. Neoplasms (Cancer) : 15 outcomes 49 studies in 365 results
  2. Ovarian Neoplasms (Ovarian Cancer) : 3 outcomes 4 studies in 10 results
  3. Acute Myeloid Leukemia (Acute Myelogenous Leukemia) : 2 outcomes 13 studies in 29 results
  4. Leukemia : 2 outcomes 9 studies in 32 results
  5. Breast Neoplasms (Breast Cancer) : 2 outcomes 5 studies in 45 results
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Drugs Related to aurora kinase

  1. 2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate
  2. Phosphotransferases (Kinase)
  3. Tamoxifen
  4. VX680
  5. MLN 8237
  6. ENMD 2076
  7. Histones (Histone)
  8. Proteins (Proteins, Gene)
  9. 4- (4- (N- benzoylamino)anilino)- 6- methoxy- 7- (3- (1- morpholino)propoxy)quinazoline
  10. imatinib (Gleevec)
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Therapies Related to aurora kinase

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Radiotherapy
  4. Immunotherapy
  5. Therapeutics
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