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febuxostat Summary

Description: structure given in first source; unlike allopurinol, febuxostat is not reincorporated into nucleotides in purine metabolic pathways and does not affect pyrimidine metabolism

Also Known As: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid; TEI 6720; TEI-6720; Uloric; 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-

Networked: 206 relevant articles (37 outcomes, 61 trials/studies) for this Drug

Key Diseases for which febuxostat is Relevant

  1. Gout : 22 outcomes 40 studies in 130 results
  2. Hyperuricemia : 13 outcomes 25 studies in 83 results
  3. Renal Insufficiency (Renal Failure) : 1 outcome 1 study in 6 results
  4. Hematologic Neoplasms (Hematological Malignancy) : 1 outcome 1 study in 3 results
  5. Reperfusion Injury : 1 outcome 1 study in 3 results
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Drugs Related to febuxostat

  1. Allopurinol (Remid)
  2. Uric Acid (Urate)
  3. Xanthine Oxidase
  4. purine
  5. rasburicase (Elitek)
  6. benzbromarone drug combination allopurinol
  7. polyethylene glycol-uricase
  8. Xanthine Dehydrogenase
  9. Benzbromarone
  10. Xanthine
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Therapies Related to febuxostat

  1. Renal Dialysis (Hemodialysis)
  2. Transplantation (Transplant Recipients)
  3. Ligation
  4. Drug Therapy (Chemotherapy)
  5. Investigational Therapies (Experimental Therapy)
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