[Comparative analysis of tests on in vitro and in vivo quantitative assessment of the immunogenicity of tick-borne encephalitis vaccine].

Abstract

Many-year routine use of EIA as an in vitro test demonstrated it as a highly reproducible and technological test for assessing the efficacy of vaccine against tick-borne encephalitis and its semiproducts at the intermediate stages of vaccine production. The reproducibility of mouse protection test is notably inferior to that of EIA.

• Authors: L B El'bert, M F Vorovich, A V Timofeev
• Journal: Voprosy virusologii (Vopr Virusol) 1998 Sep-Oct Vol. 43 Issue 5 Pg. 236-8 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Sravnitel'nyĭ analiz testov in vitro i in vivo kolichestvennoĭ otsenki immunogennosti vaktsiny kleshchevogo éntsefalita.
• PMID: 9864830 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Viral Vaccines

Topics

• Animals
• Encephalitis, Tick-Borne (immunology, prevention & control)
• Fluorescent Antibody Technique
• Mice
• Reproducibility of Results
• Viral Vaccines (immunology)